Endocrine Abstracts

Parathyroid carcinoma (PC) is a rare endocrine tumor accounting for 0.5–6% or less in cases of primary hyperparathyroidism. According to The American Joint Committee on Cancer (AJCC) eighth edition, the histopathological criteria for PC include the presence of vascular invasion with capsular invasion and progression and/or metastasis to adjacent tissues. However, the small number of cases of PC makes it difficult to predict prognosis in the postoperative period of PC. We ...

Congenital adrenal hyperplasia (CAH) describes a group of autosomal recessive disorders where the cortisol biosynthesis is impaired. There are two forms of CAH: the classic form, which includes the salt-wasting and the simple virilizing forms, and the nonclassic form. CAH due to 21-hydroxylase deficiency accounts for 95% of cases. Treatment of the classic form of CAH is targeted at replacing cortisol and aldosterone and effectively controlling excess androgen symptoms by using...

Cushing’s syndrome is a collection of signs and symptoms due to prolonged exposure to cortisol. It can be difficult to diagnose, particularly endogenous Cushing’s syndrome, because other conditions share the same signs and symptoms. Diagnosing Cushing’s syndrome can be a long and extensive process, it’s treatment may be also an important challenge. We present the case of a 49-year-old man, with a history of asthma and pulmonary cribriform adenocarcinoma (ra...